does blood type affect covid vaccine side effects does blood type affect covid vaccine side effects

Those symptoms are similar in all vaccines, but in the two-dose vaccines, they are more common after the second shot. Gundry and Anderson and their collaborators have been collecting and studying blood and tissue samples for this collaborative research. Side effects of the coronavirus (COVID-19) vaccination Very common side effects in the first day or two include: having a painful, heavy feeling and tenderness in the arm where you had your injection feeling tired headache, aches and chills diarrhoea, nausea and vomiting mild flu-like symptoms "Masks are important because they filter out some of the virus and decreases the viral load, which makes the infection less severe," says Dr. Anderson. The latest Omicron COVID-19 vaccine may lead to similar side effects caused by earlier versions, which include injection site pain, fatigue, fever and more. For A and AB groups, the stay was 13.5 days. In both trials, the most commonly reported side effects within a week of injection were: Pain at the injection site, alongside redness and/or swelling Extended fatigue Headaches Widespread. However, they did not find strong evidence for a relationship between blood group and risk of intubation or death. Patient 1 is a 25-year-old man diagnosed with PNH 6 months prior in the setting of hemoglobinuria and had limited disease manifestations not requiring PNH-directed therapy. Researchers have been talking about blood type and COVID-19 susceptibility for months. Conflict-of-interest disclosure: R.A.B. Why? If you have or suspect that you have a medical problem, contact your healthcare provider promptly. Computed tomography with contrast showed peripancreatic fat stranding with normal lipase, concerning for possible small bowel microvascular thrombosis. Typical side effects include pain at the injection site, fever, fatigue, headache, muscle pain, chills and diarrhoea. Association between ABO and Rh blood groups and SARS-CoV-2 infection or severe COVID-19 illness. After being vaccinated, it's common and normal to have temporary side effects, even after a COVID-19 infection. This preliminary safety signal has prompted additional investigation into whether . Type A blood was associated with a 45 percent increased risk of having respiratory failure, while Type O was associated with a 35 percent reduction in risk. Some less common side effects include nausea and swollen lymph nodes (especially in the armpit). Common comorbidities included preexisting cardiac disease (13-15%), chronic kidney disease (11%), anemia (21%), cancer (27-29%), dementia or frailty (33-38%), diabetes mellitus (21%), asthma (18-21%), and chronic hypertension (39-41%). If not, you can order an inexpensive kit to test your blood at home by pricking your finger to get a small blood sample, which you can then mix with antibodies to the A and B antigens that come on the card. Concerns have been raised about a particular situation whereby certain blood clots have occurred together with low levels of platelets tiny cells in the blood that help it to clot. Together, Drs. Researchers found no link between blood type and COVID-19 risk, adding that more research was needed on the topic. The studys primary outcome was SARS-CoV-2 infection. Headache. In other words, the benefits of the jab far outweigh the risks. Dr. Susan R. Bailey, an allergist, immunologist and president of the American Medical Association, said side effects develop because your immune system is reacting to the vaccine. Should you eat before? Redness and swelling at the . It's important to note that individuals will react to these bivalent booster vaccines differently while the most common side effect is pain or swelling at the injection site, many people may feel more severe side effects, and unique combinations of the symptoms listed above. Correspondence: Robert A. Brodsky, Division of Hematology, School of Medicine, Johns Hopkins University, 720 Rutland Ave, Ross Research Bldg, Room 1025, Baltimore, MD 21205; e-mail: brodsro@jhmi.edu. fatigue for 50% of the participants. Here's a list of the side effects to the COVID-19 vaccine, plus information on how experts track side effects and what reports of serious side effects mean. Patients were identified based on self-report of receiving the vaccine. This variant is associated with a 12-percent reduced odds ratio of testing positive for COVID-19.1. Youve viewed {{metering-count}} of {{metering-total}} articles this month. Blood type O seems to have the lowest risk. Patient 2 is a 45-year-old man with a 20-year history of PNH. The most common side effects of COVID-19 vaccination are not specific to diabetes. His last dose of ravulizumab was 4 weeks prior to vaccination. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. What scientists have learned is blood type seems to matter in at least two ways: Recent data suggests that people with blood type A have a significantly higher risk of acquiring COVID-19 than non-A blood types. That means getting vaccinated and boosted, social distancing, wearing a mask in public, and washing your hands regularly, among other things. Free download: Get the Body Ecology blood type ebook. A comprehensive review of studies published in Seminars in Vascular Surgery in September 2021 examined peer-reviewed journal articles published from March 2020 to January 2021. According the ZOE Covid symptom study released last month and looking only at the Pfizer jab, about a third of vaccine recipients who had previously had Covid reported having a whole-body side-effect (such as chills), compared with 19% of those who had not had Covid. However, cases remain very rare: the MHRA noted 79 cases of blood clots with low platelets, including 19 deaths, following more than 20m doses of the AstraZeneca jab, with 44 of the cases and 14 of the deaths related to a rare type of blood clot in the brain called cerebral venous sinus thrombosis (CVST) that occurred with a low platelet count. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal, or homeopathic supplement, or using any treatment for a health problem. But for young adults that equation, at least at present, is less clearcut. Virologists and vaccine experts explore what we know below. The question of a possible relationship between blood type and disease risk has been a topic of active research since early in the pandemic. This seems to be an issue with DNA adenovirus vector vaccines the biology of which is yet to be fully understood, said Prof Saad Shakir, director of the independent Drug Safety Research Unit. Briefly, type O-positive red blood cells from 1 patient with PNH and 1 control were collected. While it's not a hard-and-fast rule, CDC officers have made recommendations to Americans to consider delaying receiving this bivalent booster vaccine at least three months from the date of your last COVID-19 infection. The secondary outcome was severe COVID-19 illness or death. However, the chance of developing severe illness and death after a COVID-19 infection is much higher (2-10%). In patients with severe disease, deposition of terminal complement and microthrombosis have been observed in the lung, skin, kidney, and heart.14 Recently, we demonstrated that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein leads to amplification of the alternative pathway of complement on cell surfaces through competition with complement factor H (CFH) for binding heparan sulfate.5 Thus, in vitro, the SARS-CoV-2 spike protein can convert an inactivator surface to an activator surface on nucleated cells. "There is no real benefit for the individual person," said Torben Barington, DMSc, a clinical professor of immunology at the University of Southern Denmark and co-author of the early Danish study. Women and younger adults tend to have more side effects than men or older adults do. Yet these risks are relative, meaning people with type O blood are not immune to COVID-19. Muscle aches. Side effects in adults 60+ after Johnson & Johnson vaccine Pain at injection site (33.3%) But it's interesting to note that the severity of side effects caused by bivalent vaccines were reported as less severe; Pfizer's clinical trial found that less than 1% of patients experienced severe pain or headaches, whereas a majority of participants (52%) reported only mild pain at the injection site. The side effects of the three COVID-19 vaccines approved by the FDA for temporary use (Pfizer, Moderna and . One study of over 3,000 people who got a COVID-19 vaccine did not find any increased side effects or other issues among people with different blood types. The second study (also from October 2020) from researchers in Canada looked at data from 95 patients who were severely ill with COVID-19. Fever. They include: tenderness, swelling, and. Contribution: G.F.G. Information contained in this story may be outdated. Blood types are split up into four major groups, all dependent on the presence or absence of two specific antigens on the surface of the blood: A and B, according to the American Red Cross. Of course, your blood type is not a risk factor over which you have any control. and T32 HL 007525 (G.F.G. If any of these side effects occur, they should go away in a few days. Fatigue, headaches, muscle and joint aches and fever are all potential side effects as well. designed and performed research; J.Y., B.A.Y.C., E.M.B., and S.C. interpreted results and edited the paper; R.A.B. When compared with the first dose, adverse reactions reported after the second dose were milder and reported less frequently, the MHRA noted. "As an individual, you have your blood typethere's nothing you can do about it.". "Reassuring the public that everything is being done . Notably, she took danicopan throughout her first vaccination and did not experience breakthrough hemolysis. muscle pain . Information and statements regarding dietary supplements/products have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Immunothrombotic dysregulation in COVID-19 pneumonia is associated with respiratory failure and coagulopathy, Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19, Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition, Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine, Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine, How I treat paroxysmal nocturnal hemoglobinuria, SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2, Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome, Heparan sulphate identified on human erythrocytes: a Plasmodium falciparum receptor, Anti-complement treatment for paroxysmal nocturnal hemoglobinuria: time for proximal complement inhibition? Adjusted relative risks (aRRs) and absolute risk differences (ARDs) were adjusted for demographic characteristics and comorbidities. People with the O blood type (whether O positive or O negative) had a lower incidence of COVID-19 positive tests. Researchers have been talking about blood type and COVID-19 susceptibility for months. At this point in time, there does not appear to be any relationship between blood type and COVID-19related severity of illness or mortality.". 16 Furthermore, 3 instances of Fever or chills. If you wish to read unlimited content, please log in or register below. Dr. Gundry and her team continue to investigate how heart injuries caused by COVID-19 developand the impact of red blood cells on the infection. Indeed, coagulopathy (problems with bleeding disorders) is common in COVID-19, with dangerous blood clots being a hallmark of the disease. The risk for individuals for Type O blood appeared to be significantly lower, just 26 percent of the cases versus 34 percent of the healthy control group. Or, they suggest, perhaps the genes associated with blood type also have some effect on the ACE2 receptor, the protein that allows the SARS-CoV-2 virus to infect human cells. COVID-19 vaccine side effects can vary depending on a person's age, sex, or health. Similar disease flares may be anticipated in other complement-mediated disorders, such as complement-mediated hemolytic uremic syndrome, cold agglutinin disease, catastrophic antiphospholipid syndrome, and HELLP syndrome.17 As SARS-CoV-2 leads to a severe inflammatory state, the benefits of vaccinating patients with PNH likely outweigh the risks; however, clinicians and patients should be aware of this serious adverse effect, and patients should be educated to report any symptoms postvaccination.